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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
ODO2_HUMAN
USC-OGP 2-DE database
:
ODO2_HUMAN
ODO2_HUMAN
General information about the entry
View entry in simple text format
Entry name
ODO2_HUMAN
Primary accession number
P36957
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial; EC=2.3.1.61; AltName: Full=2-oxoglutarate dehydrogenase complex component E2; Short=OGDC-E2; AltName: Full=Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; AltName: Full=E2K; Flags: Precursor;.
Gene name
Name=DLST
Synonyms=DLTS
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
PLATELET_4-7
{PLATELET 4-7}
Homo sapiens (Human)
map experimental info
PLATELET_4-7
MAP LOCATIONS:
SPOT OGP-0367
:
pI=5.64; Mw=50345
PLATELET_5-6
{PLATELET 5-6}
Homo sapiens (Human)
map experimental info
PLATELET_5-6
MAP LOCATIONS:
SPOT OGP-0676
:
pI=5.65; Mw=50424
Cross-references
UniProtKB/Swiss-Prot
P36957; ODO2_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
ODO2_HUMAN
Primary accession number
P36957
Secondary accession number(s)
B7Z5W8 E7ESY5 Q7LDY7 Q9BQ32
Sequence was last modified on
January 11, 2011 (version 4)
Annotations were last modified on
March 15, 2017 (version 186)
Name and origin of the protein
Description
RecName: Full=Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial; EC=2.3.1.61; AltName: Full=2-oxoglutarate dehydrogenase complex component E2; Short=OGDC-E2; AltName: Full=Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; AltName: Full=E2K; Flags: Precursor;
Gene name
Name=DLST
Synonyms=DLTS
Encoded on
Name=DLST; Synonyms=DLTS
Keywords
Acetylation
;
Acyltransferase
;
Alternative splicing
;
Complete proteome
;
Direct protein sequencing
;
Lipoyl
;
Mitochondrion
;
Phosphoprotein
;
Polymorphism
;
Reference proteome
;
Transferase
;
Transit peptide
;
Tricarboxylic acid cycle
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
D16373; BAA03871.1
; -; mRNA
EMBL
D26535; BAA05536.1
; -; Genomic_DNA
EMBL
L37418; AAB59629.1
; -; mRNA
EMBL
AK289414; BAF82103.1
; -; mRNA
EMBL
AK299505; BAH13054.1
; -; mRNA
EMBL
AC006530; AAD30181.1
; -; Genomic_DNA
EMBL
CH471061; EAW81199.1
; -; Genomic_DNA
EMBL
BC000302; AAH00302.1
; -; mRNA
EMBL
BC001922; AAH01922.1
; -; mRNA
CCDS
CCDS9833.1; -. [P36957-1]
; .
PIR
S39786; PN0673
; .
RefSeq
NP_001924.2; NM_001933.4. [P36957-1]
; .
UniGene
Hs.525459; -
; .
ProteinModelPortal
P36957; -
; .
SMR
P36957; -
; .
BioGrid
108087; 32
; .
IntAct
P36957; 27
; .
MINT
MINT-3014449; -
; .
STRING
9606.ENSP00000335304; -
; .
iPTMnet
P36957; -
; .
PhosphoSitePlus
P36957; -
; .
SwissPalm
P36957; -
; .
BioMuta
DLST; -
; .
DMDM
317373578; -
; .
OGP
P36957; -
; .
UCD-2DPAGE
P36957; -
; .
EPD
P36957; -
; .
MaxQB
P36957; -
; .
PaxDb
P36957; -
; .
PeptideAtlas
P36957; -
; .
PRIDE
P36957; -
; .
TopDownProteomics
P36957-1; -. [P36957-1]
; .
DNASU
1743; -
; .
Ensembl
ENST00000334220; ENSP00000335304
; ENSG00000119689. [P36957-1]; .
GeneID
1743; -
; .
KEGG
hsa:1743; -
; .
UCSC
uc001xqv.3; human. [P36957-1]
; .
CTD
1743; -
; .
DisGeNET
1743; -
; .
GeneCards
DLST; -
; .
H-InvDB
HIX0131240; -
; .
HGNC
HGNC:2911; DLST
; .
HPA
HPA003010; -
; .
MIM
126063; gene
; .
neXtProt
NX_P36957; -
; .
OpenTargets
ENSG00000119689; -
; .
PharmGKB
PA27367; -
; .
eggNOG
KOG0559; Eukaryota
; .
eggNOG
COG0508; LUCA
; .
GeneTree
ENSGT00860000133844; -
; .
HOGENOM
HOG000281563; -
; .
HOVERGEN
HBG000268; -
; .
InParanoid
P36957; -
; .
KO
K00658; -
; .
OMA
EGKKDMK; -
; .
OrthoDB
EOG091G08FX; -
; .
PhylomeDB
P36957; -
; .
TreeFam
TF314164; -
; .
BioCyc
MetaCyc:HS04324-MONOMER; -
; .
Reactome
R-HSA-389661; Glyoxylate metabolism and glycine degradation
; .
Reactome
R-HSA-71064; Lysine catabolism
; .
Reactome
R-HSA-71403; Citric acid cycle (TCA cycle)
; .
UniPathway
UPA00868; UER00840
; .
ChiTaRS
DLST; human
; .
GeneWiki
DLST; -
; .
GenomeRNAi
1743; -
; .
PRO
PR:P36957; -
; .
Proteomes
UP000005640; Chromosome 14
; .
Bgee
ENSG00000119689; -
; .
CleanEx
HS_DLST; -
; .
ExpressionAtlas
P36957; baseline and differential
; .
Genevisible
P36957; HS
; .
GO
GO:0070062; C:extracellular exosome
; IDA:UniProtKB; .
GO
GO:0016020; C:membrane
; IDA:UniProtKB; .
GO
GO:0005759; C:mitochondrial matrix
; TAS:Reactome; .
GO
GO:0043209; C:myelin sheath
; IEA:Ensembl; .
GO
GO:0005634; C:nucleus
; IDA:UniProtKB; .
GO
GO:0045252; C:oxoglutarate dehydrogenase complex
; IEA:InterPro; .
GO
GO:0004149; F:dihydrolipoyllysine-residue succinyltransferase activity
; IEA:UniProtKB-EC; .
GO
GO:0006091; P:generation of precursor metabolites and energy
; TAS:ProtInc; .
GO
GO:0046487; P:glyoxylate metabolic process
; TAS:Reactome; .
GO
GO:0033512; P:L-lysine catabolic process to acetyl-CoA via saccharopine
; IEA:UniProtKB-UniPathway; .
GO
GO:0006554; P:lysine catabolic process
; TAS:Reactome; .
GO
GO:0006099; P:tricarboxylic acid cycle
; TAS:Reactome; .
Gene3D
3.30.559.10; -
; 1; .
InterPro
IPR003016; 2-oxoA_DH_lipoyl-BS
; .
InterPro
IPR001078; 2-oxoacid_DH_actylTfrase
; .
InterPro
IPR000089; Biotin_lipoyl
; .
InterPro
IPR023213; CAT-like_dom
; .
InterPro
IPR011053; Single_hybrid_motif
; .
InterPro
IPR006255; SucB
; .
Pfam
PF00198; 2-oxoacid_dh
; 1; .
Pfam
PF00364; Biotin_lipoyl
; 1; .
SUPFAM
SSF51230; SSF51230
; 1; .
TIGRFAMs
TIGR01347; sucB
; 1; .
PROSITE
PS50968; BIOTINYL_LIPOYL
; 1; .
PROSITE
PS00189; LIPOYL
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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